I friggin' LOVE Dr. Mario - he was way better to play as in Melee than Vanillio.
I love how psychopathic the implications of him in Smash are too - some alternate universe version of Mario decided to go into pharmaceuticals before taking a vacation to try and get his doppleganger (and co) to OD on powerful prescription drugs.
You see, the good doctor HAS no friends. He is alone in his universe. And he is here to unleash the mightiest of wraths upon your nervous system.
First comes paralysis. Then comes cardiac arrest. Before the final blackness hits, you feel one last horse-dong sized "vitamin" being shoved down your throat, and your last experience in the mushroom kingdom is a simultaneous mixture of suffocation and full CNS shutdown.
Wahoo motherfucker, time to practice my medicine