I don't plan on playing this game, I don't watch animes, so I'm here for the anthropological point of view and because XCom 2 are still 2 weeks away, so, you know, ignore me if you will. But this is how I see this discussion going:
The female character quacks like a lesbian and hit on girls like a lesbian, but she isn't a lesbian because the game blocks her from dating other girls using the in-game dating mechanics. So, she likes girls, but she can't like-like girls, not for realsies, just as a gag.
The magical drug thing is the most contrived plot device in history and makes the character sees all male characters as females, a male character, who is interested in this absolutely not-lesbian, but yeah kind of lesbian girl uses this, without her knowing, to the primary purpose of being more attractive to her, since she is attracted to girls, except she is not a lesbian, so he is using that to... teach her how... to be less nervous around the girls she is not attracted to.....?
So, she falls in love with the female version of this male character, yet not being a lesbian, when the drug is out of her system, she sees the world as it should be and, therefore, couples with a man, as it should be. Her problem of not really being a lesbian, but really liking girls is solved.
This is not offensive to the LGBT community because she was never a lesbian, she only liked girls, but not like-like, she could even marry other guys without the magical drug episode, so she never liked-liked girls, only liked girls, but never was a lesbian.
The drug, slipped into her drink without her knowing and making her see her male friend she doesn't care about as someone she is attracted to, thus giving him a chance she was neurotically denying him, thus proving that not liking him was a wrong mindset that therefore was fixed, has nothing to do with a roofie.
But in all of this there is a lot of mistranslations and misuderstandings because Japan is this weird land far far away with different values. Their homossexuals... well, I don't know what their homossexuals think or what they do or how they feel, they don't matter, the thing is: to make fun of them is absolutely normal there; the point that they don't have organizations strong enough to enact the changes that we see here are proof that everything is ok with LGBTs in Japan. According to a poster here, there is even a blackfaced character, and the lack of controversy around that clearly shows that there is no racism in Japan, either.
So, Nintendo looks at all these mistranslations and misuderstandings and decide to censor, which is that dictatorships do, so it's bad even if we are admitting to interpret the word in a way that makes it no so bad, the story that innocently shows a lesbian who is not a lesbian being magically drugged by not a drug into seeing her male friend as a female and realizing, through that process, that she can not be the lesbian she never was, being, therefore, cured of her affliction which was liking girls, but she was never a lesbian... ok, I lost it. That story is now censored. And it shouldn't be, because we live in a simple world where censorship is always bad, even when I interpret the word in a way to make it as any change done by a concerned creator is censorship.
When a creator censors their own material because either they, themselves, have certain values that certain things are wrong or offensive or because they are presenting this work to a society that believes this kind of material breeds violence, that creator is a victim of self-censorship, which is a form of peer pressure that happens when a politicallly driven group voices concern or outrage over a material; which concerns and outrages people because their politically driven group was fine with the political message that existed before the censorship occured.
...XCom 2 needs to release soon.