Among the inquisition perks, what's should I get first? I'm already done with Wicked Eyes and Wicked Hearts yet I haven't even touched my perks lol I guess I'll look into more on my 2nd playthrough.
Extra healing potions (going from 8 to 12) is the most useful gameplay-wise by far. It can be a lifesaver on higher difficulties, and if you have party members (like Iron Bull or Cole) with low defense.
After that, I don't remember many being essential. The Deft Hands perk is nice to get early if you like exploring everywhere and don't want to bother having to travel back to an area later in the game just to unlock one room in a dungeon (most locked rooms usually just have loot, though some have mosaic or other collection items).
The "knowledge" perks in all categories, which give you conversation options and extra XP for codex entries, are good to get early too. They open up more conversation options and let you resolve some quests in different ways. The XP bonus is minimal though (25XP for each codex entry for each perk you have; they stack).
I got the Antivan Tailoring perks relatively early too, because I like to loot everywhere and my inventory was constantly reaching the limit, and I hate deleting gear.
After that I got a mix of Advanced / Master Focus, carrying a third potion, and various experience / defense buffs. Never bothered with schematics, store discounts, or materials.
I think by the end of my run I'd reached Inquisition level 17, so you should have lots of points to play with to pick and choose.
EDIT: I forgot, if you tend to gather a lot of herbs for upgrading potions, etc., get the Optimal Cutting perk. I think it has a 10% chance of triggering when you gather an herb, but if it does trigger you usually get anywhere from 1-9 extra herbs, which can save you a bit of time.