I don't think that's a big enough drawback for a card as powerful as Timetwister. Especially with hand emptying in certain formats.
All this discussion is moot though. This is a huge issue for a collector such as me. If Wizards is going to make one change to all the cards on the do not print list and then reprint them, I'm out.
1. They've been doing it for years. The Power 9 still grows in value due to age, scarcity and notoriety, not just power. Some examples that probably should have made you quit a long time ago if this is how you feel.
- Treasure Cruise
- Temporal Mastery
- Lion's Eye Diamond
- Lotus Petal
- Lotus Bloom
- etc
2. They're going to reuse design space occasionally, especially powerful effects that make people excited. Again, this isn't going to crash, or even impact your collection's value. They aren't going to lock away the effects of powerful cards, just likely the most broken and/or powerful applications of them.
3. I think you're wrong about this one. Refilling your opponent's hand and then giving them the turn right away is likely a huge disadvantage.