My Destroyer is only 4* so I can't say how he is at 6*, but I can't imagine him being anywhere near Ronan, uVision, Throot, or Ultron to call him top tier. He doesn't have a 6* skill, his regular skills aren't that great (except for the stun), his passive sucks, and his leadership sucks.
Captain Marvel is better as she at least has a use. Her leadership in VS as another boost to Blast characters and she's female for BW. Angela is also better due to damage. The rest of the Universals are indeed awful so I'd rank him in the middle.
Hey all, very new to this game. Is there a tier list or something I can look at to figure out who to recruit? Currently running Iron Man, Spiderman, and War Machine, but I've only just entered the chapter 2 levels
Warmachine is the 2nd best character in the game (imo). Get his uniform. I use Yellow Jacket, War Machine, and Vision (with uniform). I start off with YJ as lead, but typically switch in WM as he just tears through missions. He can take the last level rather easily and I never really bothered to get his ISO-8 or gear levels too high. He dishes out a lot of damage, has a good life pool, his auto attack hits extra hard, has a break (or stun with uniform), three of his abilities auto track, and l his animations have him gliding around the battlefield out of danger. He's really easy to farm too so your focus should be on him. He will get you through the entire game.
Spidey is great. I debate often who is the more annoying speed character to fight in Timeline Battle or Battleworld between him and Green Goblin. The short cooldowns, long stun, and invincibility frames are amazing. He kind of sucks for auto-battle story mode (Black Widow is really the only speed character I like there). He really shines only in the "PvP" modes. Either way you really only need one carry and Spider-Man is worth leveling as you will do PvP eventually.
Iron Man is good, but a solid tier below those two. Still, all Blast characters are worth leveling. This game has an abundance of popular Combat characters and Villain Siege is full of them too. Having more Blast makes it a lot easier to clear VS. He's better with his costume (but he loses some speed). He's super easy to farm too.
My advice starting off would be clear as much as you can focusing on War Machine. When you can spare the energy, aim for Vision bios too as with his costume, he pulls double duty and is right up there with WM. Save all crystals for costumes for when they come back on sale. Don't spend crystals on energy, arena entries, retries, or gold. Uniforms are limited while everything else is always there or a bad value. Try not to use clear tickets when starting out, you need the shield XP to raise your energy cap.
Another option is dump Iron Man and go for Venom bios. War Machine, Spider-Man, Venom is an awesome starting combo that does well in both Story and Arena. War Machine's leadership is great for everyone on the team and you will hit every type (minus Universal) to gain pokemon bonuses. Spidey and Venom have a very good team bonus compared to the War Machine and Iron Man one. Venom (especially with his costume) is a better Combat character than Iron Man is a Blast. Zombie Venom at 6* is so annoying to fight with his constant hit stun, breaks, and fears.
If you find yourself finished farming the missions you can with those characters and have spare energy, clear the special missions for Yellow Jacket and Goliath (Ant-Man special mission 3 and 4). YJ is the best character in the game and both are super easy to obtain.