Finally started this a few days ago (360). Terribly lttp, but ME is one of those games you have to sink your teeth into and now I can give it the attention it deserves.
So eh, wow. I really can't begin to describe how impressed I am. So far not only has Bioware ironed out most of the ME-kinks, but in the process delivered one of the most polished games I've played recently. The performance is just way, way better and I'm so glad they removed all the moonbuggy sections. It's just a complete joy to play now and a pretty seamless experience at that!
A friend of mine was a bit disappointed in the game because of the general streamlining and removal of rpg-elements but so far I don't feel the same. I'd complain if the overall experience suffered, but somehow the extreme streamlining works. This game is still all Mass Effect, only now without the terrible inventory system and copy paste planet exploration. Combat works a lot smoother now that the devs have just fully embraced that it's a shooter with some spell casting. Glad I don't have to bother with changing ammo types every few encounters. Yeah it's even less of an rpg now, but it wasn't as if ME1 was the deepest rpg to begin with. They just kept what worked and threw the flawed elements in the trash insteading of changing them. It worked.
The depth remains where needed and by this I mean the world and characters of course. ME2 succeeds to draw you into the world even more than the first game. I'm way more invested into my party members and their specific sidequests have been amazing so far, even better than the main quests tbh. Completed Jacob and Mordin's loyalty missions and it seems a lot of work went into these. I've accepted all of my party's personal quests and I intend to sit through all of them before returning to the main quest. They're pretty much a must if you want to know your crew better.
The only baffling inclusion is the scanning/probing of minerals. Shit gets old fast and I'd guess it's been brought up here numerous times, but still. Weird that Bioware didn't feel this'd get stale in a heartbeat. Still, it's way better than exploring 100 samey planets and digging up stuff there.
I've only played for 10 hours, so it's a bit early to dish out this kind of praise and I'll see where the story goes, but gameplay-wise... It's a massive improvement over 1.