Sorry, I haven't been following the farming strategies in this game too closely duei to being a silly casual but... let me get this straight.... once a named boss outside the DZ is killed, they are gone forever and you can no longer farm them for their unique weapons? And the reason they did this is because people were farming them over and over again for said weapons?
HAVE THESE PEOPLE NEVER PLAYED A FUCKING RPG BEFORE?
I can't think of a loot game where I DIDN'T do that. Hell, I can't even remember how long I farmed bosses in Borderlands 2 before I had every damn legendary item in the game. And to do that, you killed the bosses over and over and over again.
If the problem was pheonix credits, just don't have them drop after the first kill. But the items... fuck.
I'll probably never ever ever see a Caduceus now. Sucks to realize this stuff so late.