TVHM + DLC really shows the deficiencies in this game's design. The enemies are complete bullet sponges which wouldn't really be an issue except your complete inability to carry a useful amount of ammo or effectively generate your own. It has gotten to the point where I die in the middle of encounters just so I can go and pick up some more ammo.
I don't really understand. Helpful tips, though. As someone who never struggled for a second in TVHM (except in the rare instances when they give the enemy bullshit rocket launchers):
1.) Take quests on when they're listed as "Normal". If you take on "Tough" or "Hard" quests, it means that your level and items aren't high enough to make it reasonably easy to manage without expending lots of ammo along the way. At "Tough" and "Hard", they're bullet sponges. At "normal", not so much. Go out into the countryside and farm rabid animals n' shit until you level up some. FWIW, I did most of my most recent TVHM run with almost every mission as "Tough". But that's because I felt Mechro needed the extra challenge. It wasn't Halo on "Legendary" hard, but it was definitely similar. Lots of kiting and dancing required.
2.) SMGs and AR's expend a lot of ammo, with relatively little return, imo, unless you have a really powerful one. If you're looking for impressive damage, play with shotties, pistols and sniper rifles. Get some Jachob's SR's and pistols of level equal to your current level and profit. Also, headshots are your friend. IMO, AR's and SMGs are only worth it with a really OP relic or class mod (like the +95% SMG damage I have for my Siren in a class mod).
3.) Take. Your. Time. Rushing through areas where enemies spawn decrease your ability to crowd control. Crowd control is essential for obvious reasons. There's no countdown limiting your time to finish a mission 95% of the time...so go easy, enjoy the scenery, and stay alive.
4.) If you're running out of ammo...and assuming you're turning in Eridium for ammo cap upgrades...switch to a different weapon type? It's pretty hard to run out of ammo mid-mission anyway (I found it only happens if the mission is "Tough" or higher), but if you're doing it, switch weapon types for awhile.
5.) Open everything. No exceptions. Ammo is an issue? Ammo comes in stuff that can be opened.
6.) Take really problematic enemies out from long range. Every time.
7.) Always have a good shotty for the Threshers in the Caustic Caverns. Nothing else drops them fast. Don't use an SMG. Don't use a pistol. Use a Shotgun or a RL. With strong preference to the Shotty.
8.) Know where the crit areas are on enemies (like the red eye on Constructors, arm joints on regular robots, etc.) and peg them repeatedly with high-damage weapons.
9.) Kite better. This starts with assassinating as many enemies from afar with your SR as possible. Thin the numbers. Makes life easier.
10.) Weaken wild animals with the weapons on vehicles, then get out and kill them to get full XP from the kill. And of course, you save a ton of ammo.
11.) Even if you die, it's not like money matters in BL2. Everything just scales to how much cash you have.
12.) Don't start a mission without full ammo. If you're too cheap to just buy ammo, go to Sanctuary, open everything, save --> quit --> go back to Sanctuary and do it again and again until you're max ammo. However you do it, don't go out without max ammo. Also, consider ammo-boosting relics. I have relics that give +55% ammo on 2 or 3 weapon types. Keep killing everything and opening everything and you'll get some of those.
13.) Dump those old favorite items. Any weapons/shields/nades that are more than 2 levels below your current level are hurting your progress and making current difficulty missions harder. Dump them as soon as you can find an upgrade. If you can't find one fast enough, use a golden key or two. Put those old weapons in storage, mule them to another character, whatever. But move on.
I can count on my hands the number of times I died in TVHM, and that's how I went about it 3 times now. Figure out where you're deficient (weapon quality, headshot consistency) and fix it. The problem isn't TVHM. The problem is something you're doing or not doing, or the weapons you're doing it with. gl.