You know, I think Denis is just a guy who isn't happy with just sitting back, making his game, and telling people how good it is. He has well-thought-out (though misguided, IMO) opinions about things in the gaming industry, and he wants to talk about them. And if there's anything I'd like to not see in this thread, it's these "When will MS shut him up" posts, because I'd much rather have developers who actually speak their minds than just a lot of salesmen.
I still feel that Denis makes several good points, but it is lost in what I believe to be his misguided view of the place of message boards. Of course he takes NeoGAF too seriously, and that's unfortunate, especially for him, but it's not realy crazy to think that he might start taking things seriously after a while. It's no different from school, when you have a lot of kids making jokes about one kid. To them, each of them is making a little joke about the kid, no big deal. To the kid, it's him against the world, and everyone's out to laugh at him. So when Dyack comes onto NeoGAF and sees people being encouraged by moderators to mock the game he's put years of his life into, sees people photoshopping him into hamburgers or posting screencaps of his status when he lurks, I think it's reasonable to think that it gets to him. I mean, in the end, it's really about perspective. A lot of people bash him and/or the game for fun and making some jokes... or maybe letting off some steam. But to him, it looks like a lot of people hating on a game that he's worked on for years and they've never played. And he can't understand it.
So in conclusion, it's really simple: everybody but the target of the joke can see that it's a joke. It's not really some awful thing worth getting worked up about from either side.
For his own sake, I hope Denis realizes that GAF is about entertainment and up-to-date news, and he should try not to take things personally. There are a lot of people on this board who really hope that Too Human is an excellent game.
Also, I believe when Dyack refers to GAF as "The NeoGAF," he's saying it in the same way some might say "some GAFers." It's to reflect a large group of members on the site.