I don't see hybrids to be effective. At least initially. The strength / int investment is just too high to get rid of the penalty. Not to speak of the missing boni. Talents also need to be spread out more.
I can see it working of you just want one spell from the starter choices (e.g. +50% dmg buff, or Retreat from the Ranger), other than that, I don't think it'll make for a strong character.
I'm going for a Melee with the following skills / talents / traits and make him an onslaught meat wall machine of impenetrable doom and swift death. Since my other character has Leadership and a damage buff, he's dishing out ridiculous damage.
In my testings, I was dishing out out up to 60 damage per normal melee swing on level 1 WITHOUT Bully active.
I'll be focusing on 2 Handed, Armor prof, Blacksmithing (just for the upgrading, not so much for weapon creating). Charisma (for dialogue options / intimidation) and Man-at-Arms. Later Bodybuilding. Due to Lone Wolf I get more talents per level up, so I can reach higher skill levels faster and easier. I'll probably change Charisma to Leadership or skill that later, since it's an easy permanent buff - even just on level 1 for my other character.
My other character will be a pure Mage that fulfills both, a supportive and offensive role.
+50% damage buff for my main character, heal, later more CC and offensive spells and a spamable slow to trigger Bully for another +50% damage increase for a whooping 150-160% damage increase (depending how stuff is calculated) along with Leadership for my warrior. Will focus on Witchcraft for buff / debuffs, Air for Damage and Utility and Water for Heal, CC and Utility. Otherwise on Lorecraft and Leadership for additional permanent boni. +Range talent and Bully for self +50% damage buff on CCed targets.
I'll probably pick up a Archer companion later, which I'll give Rogue talents such as Lock and Pocket picking as off DPS and additional source of CC / Debuffs. I'm also playing with the idea to just play with both main charters and give her Lone Wolf as well for an even greater challenge. I'll be missing the additional story of all the companions, tho.