yeah I'm familiar with the game, but never have I heard someone put it in the same vein as borderlands or diablo in terms of being loot focused.
Loot definitely is a big part of it too. There is no RPG-esque leveling or stats, so pretty much everything is based on your own skill or equipment. Finding stuff like artifacts helps you get through certain anomalies (areas that have some event that will mess you up walking through it, like electricity running through a tunnel, or a tornado, or an area where the wind would smash you on the ground)