Being all first person has already killed it. I don't care what kind of shit they try to come up with, gaming mechanics have forms and limits. It is impossible to do RE proper in first person. Other people may not mind and try to say oh I'm wrong if it ends up being a good game, but good game or not this will be throwing away what RE is for something else and I completely disagree that 4 or 6 did that.
As for other worries, like the other aspects of gameplay being all wrong, tone/style being all wrong, the setting/story/characters being all wrong, I haven't made let alone committed to any claims on that, although what is seen here and what is said by Capcom is extremely worrying. People saying RE "needed" this aren't really coming off like people who liked the franchise much. I loved everything about it, primarily the action/sassy/campy/horror style of world and characters they built with consistency. While going first person sucks, that can just be one title; if they end up throwing out the style/world/characters as well, they are pretty much killing the franchise while keeping the name.
Some people feel that happened with 4 or 6, but as I said I completely disagree with it. Those brought development on all fronts, not a change into something else from what makes it what it is. Since so many on GAF so often seem to assume I'm attempting an objective argument when I'm not, please be aware that people can go ahead and disagree about whether or not this is a "legitimate" RE and that neither of our opinions are objective reality. Nothing I'm saying is some kind of objective declaration on the game for quality as standalone or whether or not people will or should enjoy it or consider it RE. You can think and enjoy whatever the fuck you want. I'm just saying what I think from my own view of what makes the essence of franchise and how this seems in comparison.