It's a valid question because every single time one of these threads pop up, I rarely see any good conversation, I just see a lot of exasperated defenders expecting their arguments to be self-evident.
I don't really think your examples of reduction display anything. The problem that one could have with The Last of Us is that the plot is already pretty reductive. It's a short story told over many hours, with character development used to fill in the gaps. It uses a lot of TV show ideas to do that, but the real gist of the plot is basically Children of Men remixed - and you don't have to reduce the plot to prove it, it's pretty obvious in the details. Not to say that's a bad thing, it's just, well, that's what the game wants to be. The plot is a vehicle for the characters.