DonkeyPunchJr
World’s Biggest Weeb
Maybe Trump will finally get his Nobel Prize in the field of medicine, for discovering the cause of autism.
#TeamIvermectin
Charlie Kirk assassinated at Utah campus event
- Thread starter HeisenbergFX4
- Start date
#TeamIvermectin
Kacho
Gold Member
To be fair, I was lying about my love for Tylenol. I'm definitely team Advil but it doesn't give me autism.
SEGAvangelist
Member
It doesn't destroy my stomach like anti-inflammatories. I need to lay off using it too much, though.
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The Mad Draklor
Member
Ibuprofen and other NSAIDs that inhibit cyclooxygenase will inhibit the production of prostaglandins which are responsible for maintaining the protective lining in your stomach. It's why there are warnings of stomach ulcers on the label.
Tylenol uses a different pathway, but the intermediate compound during metabolism is toxic to the liver.
SEGAvangelist
Member
I know why they destroy my stomach, but thanks for letting others know. Haha. For real, though. NSAIDs are rough, and people don't realize how over time they can really cause gastro issues.
The Mad Draklor
Member
Yeah, and that's just the tip of the iceberg. For instance, because the prostaglandin production is inhibited, the precursor compound, arachidonic acid, will end up converting into leukotrienes which will worsen allergies.
Gp1
Member
It isn't that hard to exceed the maximum recommended dose on Paracetamol at all specially in these heavy flu cases. Even with 325mg pills. That's why it's considered that Paracetamol dosage is more "adjusted".
I'm more team ketoprofen for when shit hits the fan (docs here recommend it for orthopedic injuries a lot, but ibuprofen can make it up for it in mild cases) and dipirone for anything else (which is banned in US, for reasons). Both are available without prescription in my country.
But remember guys this is not a medical advice, it's just what works for me. And "winners don't use drugs!" (Like the arcade in 80/90's)
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Back in the "early" days of the opioid crisis it was Percocet causing problems. 2.5-10mg oxy but always paired with 325mg acetaminophen. So folks might work up to 3-4 10mg oxy/325mg tylenol pills a 'hit' and be ok, but then they got a batch of 2.5mg oxy/325mg acetaminophen and would take 15-20 pills to get the same oxy hit but now they were waaaay into liver damage dosing with the tylenol. Soooooooooooooooooooooo dumb to combine those meds into a single pill even if the pain relief effect was somewhat synergistic.
I have the somewhat heretical opinion that low dose, but consistent quality, oxy should be available over the counter so opioid addicts can get it and apply a safe sliding scale of use to prevent ODs. It isn't really that different from alcohol addiction, probably overall safer to use with fewer ancillary side effects (drunk driving and sexual assault, for example).
ChuckeRearmed
Member
All those countries have something in common - until recently. Homogeneous population, somebody else is inventing and developing infrastructure, somebody else is maintaining the military...But looking now, when the population has become less homogeneous and countries like EU has to ramp up their spending, while the factories like China are unable to produce goods cheaply anymore it does not look that shiny anymore. Not to mention the prime example of the mess is Canada.
SEGAvangelist
Member
Do you have a link to anything about the allergy portion? I'm curious to read it.
Trilobit
Absolutely Cozy
I consider myself Surgeon of Games and VNs thank you very much!
The Mad Draklor
Member
It's hard to find a paper that explicitly discusses the link between NSAIDs to allergies and is not locked behind a paywall, but you should at least look at Figure 1 of this paper. If you want something more visual, Medicosis Perfectionalis's video on the arachidonic acid pathways is really good:
laynelane
Member
That's very interesting. I used to take anti-inflammatory medicines (aspirin, prescription, etc.), but had to stop due to an allergic reaction to all of them (I also have a lot of allergies). Now I'm stuck with acetaminophen with codeine for chronic migraines where, in actuality, anti-inflammatory medication would work better.
A shared culture is CLEARLY the most important aspect of success for a nation, business, or even family. And culture often heavily aligns with other, less mutable, characteristics like ethnicity, birthplace/upbringing, religion, etc. So all the "Diversity is our Strength" folks TOTALLY overlooked that CULTURAL DIVERSITY is absolutely TOXIC to an organization, at almost every level, unless it's clustered (ie IT guys have their culture, HR has theirs, floor workers have theirs) and the 'superficial; diversity like race, gender, sexuality, etc is irrelevant if the broader culture is shared, For example, a football loving gay asian guy is gonna find a lot more inclusion with straight white 'football loving' people than a 'football hating' cishet straight woman with the same group of guys. The identity politics markers are far less important than the DEI folks want to admit and its the shared culture of work ethic, comradery, humor, holidays, and entertainment touchstones that allow for better teamwork, shared effort to accomplish goals, and uniting under one vision.
Barakov
Member
Stupidity, Social Media And Natural Selection go hand in hand it appears.
falconhoof
Member
Dallas ICE shooter spent SEVENTEEN THOUSAND hours playing video games
Joshua Jahn, 29, opened fire on the Immigration and Customs Enforcement detention camp in Dallas about 7am on Wednesday before killing himself. He became a loner video game addict before attack.
So far no Trans Furry Love Sex Farm Sim 3, but dem viddya games gonna corrupt the kids. The pathway from raising digital dinosaurs and hitting trees with rocks to terrorizing government agents is pretty clear now.
Can't possible be due to any anti-depression meds or anything like that...nope, dem games.Dallas ICE shooter spent SEVENTEEN THOUSAND hours playing video games
Joshua Jahn, 29, opened fire on the Immigration and Customs Enforcement detention camp in Dallas about 7am on Wednesday before killing himself. He became a loner video game addict before attack.www.dailymail.co.uk
So far no Trans Furry Love Sex Farm Sim 3, but dem viddya games gonna corrupt the kids. The pathway from raising digital dinosaurs and hitting trees with rocks to terrorizing government agents is pretty clear now.
I called this a few weeks back with the Charlie Kirk shooting, games being 'accused' of lowering the psychological bar to violence AND providing some semi-realistic training on how to commit it. They will be going for TV/movies next, maybe that Savant show is an early 'victim'.
