So I've only had a little while to play the game so far, never played the original. I jumped in for a quick round before I was about to do some other stuff.
An hour later, after collecting a whole herd of familiars and some cool upgrades, then walking over some randomizer dice type floor thingy I ended up with an entirely different set of upgrades, unlocked Azazel (my most highly anticipated character from the cast!), Cain and beat Mother for the first time.
I freaking love this game. I'm tired and half asleep, The Crew beta and FF XIV free weekend are up, both of which I want to play, Blizzcon is in full swing, and BoI isn't going anywhere, but I'm still having a hard time resisting 'another quick round'.