I'm warming up to Symmetra on Anubis B defense. I mean, I was always warm to it, but it's reached the point where I'm trying to cancer it up as much as possible. I almost never lose it anymore. This is what I do:
Shield Generator behind the point, of course. One (and only one most of the time) turret with the generator itself. The rest I spread on or near the point, depending on the enemy team loadout. I always put turrets 2 and 3 on the pillars adjacent to the point and the front entrance. Turrets 4 and 5 I put on the far ends of the point, one by the bricks near the stairs up from the ravine. and the other on the pillar by the right entrance.
The last turret's position varies depending on the enemy loadout. If they have a Tracer, I'm usually placing it on the pillar in the dark, right entrance. (this is usually where they attack from, although my general procedure as Sym on this map is to just eye all the entrances while shooting out shields and orbs down main) The idea here is to detect Tracer early and together with the other turret directly by the entrance, stop her from just triple blinking in and Pulse Bombing the generator. For any other loadout, I usually place a second turret with the generator to help protect it in a scramble if the enemy team should happen to make a clean break in.
I keep the general location of all these turrets the same most of the time but I usually slightly vary their height and orientation so enemies need an extra, split second to locate them. It's really awful for the attacking team.