My final thoughts:
This is a very meaty game. Total playtime was 19 hours on Hard, with about 17 of that actual gameplay and 2 from trying to solve puzzles (and failing) and using photo mode. I got 50/109 treasures and about half of the journals, notes, and optional conversations. If you are playing on Normal, which I strongly recommend, and just play for the story and gameplay (no treasure searching, etc), it will take you about 14-16 hours. This is as long, if not longer, than The Last of Us.
My main concern going into the game was the tonal change due to the new creative director, but it turned out to be unfounded. This has all the hallmarks of previous Uncharted games: awesome gunplay, platforming, banter, set pieces, and best-in-class graphics. This game has the most set pieces of any Uncharted game, so you can ignore whoever said otherwise. There are more serious elements than we're used to seeing in Uncharted games, but they enhance the story and make you feel like you're actually doing something for a purpose. You're not just a treasure hunter or a mass murderer (heh).
The pacing issues that I felt hamstrung the first parts of the game thankfully disappeared soon after and did not reappear. There is only one spot near the end that featured waves of enemies, and that was only frustrating because I was playing on Hard. Other than that, this game had the perfect amount of enemies at all times.
The rope mechanic is incredible. It adds a whole new layer to not only traversal but also combat. It's thrilling to use every time you have the chance, and thankfully there's hundreds of chances. There's also multiple ways to attack every encounter and platforming segment due to the rope capabilities. It's a real treat.
The only thing I didn't like about the game was the soundtrack. There's music, yes, but none of it is memorable in any way. It's merely serviceable. I can listen to Uncharted 2's soundtrack and immediately know where the music played in the game. I can also throw it on just to chill out and relax. I can't say the same for this game. Huge disappointment there.
At the end of the day, I still prefer Uncharted 2 because it's a tighter story with an infinitely better soundtrack and a better cast of characters. And since it's a shorter game, it's easier to replay. I can't see anyone replaying Uncharted 4 unless it's for trophies. It just doesn't have the same flow as Uncharted 2.
Now, on to the multiplayer where I'll spend the rest of my life.