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Ebola vaccine with 100% success rate developed

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chadskin

Member
The world is for the first time on the verge of being able to protect humans against Ebola, the World Health Organization (WHO) said on Friday, as data from a trial in Guinea showed a vaccine was 100 percent effective.

Initial results from the trial, which tested Merck and NewLink Genetics’ VSV-ZEBOV vaccine on some 4,000 people who had been in close contact with a confirmed Ebola case, showed 100 percent protection after 10 days.

The results were described as "remarkable" and "game changing" by global health specialists.
http://www.reuters.com/article/2015/07/31/us-health-ebola-vaccine-idUSKCN0Q51FP20150731

Hooray, science!
 

SgtCobra

Member
IMAAVqC.gif


Here's hoping it really fully works on those infected.
 

Goro Majima

Kitty Genovese Member
I probably haven't been paying attention but it seems like it's been a while since we've had some awesome vaccines come out. This is huge.
 

guggnichso

Banned
Here's the paper if anyone is interested:

http://www.thelancet.com/pb/assets/raw/Lancet/pdfs/S0140673615611175.pdf

Between April 1, 2015, and July 20, 2015, 90 clusters, with a total population of 7651 people were included
in the planned interim analysis. 48 of these clusters (4123 people) were randomly assigned to immediate vaccination
with rVSV-ZEBOV, and 42 clusters (3528 people) were randomly assigned to delayed vaccination with rVSV-ZEBOV.
In the immediate vaccination group, there were no cases of Ebola virus disease with symptom onset at least 10 days
after randomisation, whereas in the delayed vaccination group there were 16 cases of Ebola virus disease from
seven clusters, showing a vaccine efficacy of 100% (95% CI 74·7–100·0; p=0·0036). No new cases of Ebola virus
disease were diagnosed in vaccinees from the immediate or delayed groups from 6 days post-vaccination. At the
cluster level, with the inclusion of all eligible adults, vaccine effectiveness was 75·1% (95% CI –7·1 to 94·2;
p=0·1791), and 76·3% (95% CI –15·5 to 95·1; p=0·3351)
with the inclusion of everyone (eligible or not eligible for
vaccination).
 

TheMAK

Banned
Got to be kinda sad about this tho... this only exists because countries outside of Africa where feeling threatened by the recent outbreak so they finally decided to throw money at the scientist to develop a cure. But when that shit only affected African or other poor populations not fucks were given.... as usual... see the space race... scared of the USSR/ USA..let's to amazing shit (go in space, to the moon etch)
 
And yet this won't do much at all for the people in Africa. Look at all the diseases that are easily preventable and treatable that still exist in multiple African countries.
 

dramatis

Member
This is pretty good news. Even if the success rate drops in subsequent trials, it'll still be very helpful in preventing outbreaks as severe as the one last year.
 

hokahey

Member
Got to be kinda sad about this tho... this only exists because countries outside of Africa where feeling threatened by the recent outbreak so they finally decided to throw money at the scientist to develop a cure. But when that shit only affected African or other poor populations not fucks were given.... as usual... see the space race... scared of the USSR/ USA..let's to amazing shit (go in space, to the moon etch)

You really think this all happened in that short a period of time? Uhhh
 

kess

Member
So..? African countries didn't have the medical infrastructure to create an Ebola vaccine. The fact that it exists is good for everyone.
 

bathsalts

Member
Got to be kinda sad about this tho... this only exists because countries outside of Africa where feeling threatened by the recent outbreak so they finally decided to throw money at the scientist to develop a cure. But when that shit only affected African or other poor populations not fucks were given.... as usual... see the space race... scared of the USSR/ USA..let's to amazing shit (go in space, to the moon etch)

Cant wait for Americans to start seeing cases of cancer in their population than, come on man this is a great break through.
 
How can they create such a vaccine so quickly but for other killers not?

It always makes me suspicious.

I haven't read the paper yet but it's complicated. For one thing with something like say HIV it mutates so quickly that a vaccine would be useless by the time it was developed

Also developing something like a cure for cancer is near impossible because of how many forms it takes and how many ways it can happen
 

samn

Member
all it took was some western scare to care

There was never any point in spending tens of millions (or more) developing a vaccine for a disease that only affected a few dozen or hundred people a year. What changed is that it killed many thousands.

The west was never threatened by ebola.
 

guggnichso

Banned

This has nothing to to with the absourd proposition that there might ever be a vaccine in the traditional sense against cancer.

Also, cancer is not a word that describes a single disease. It instead describes a plethora of diseases that share common traits (see Hanahan, Weinberg; "Hallmarks of cancer"), but reach those through completely different means (different mutations compromising different or same pathways in the cells in different ways).

While people are actually working on so called "cancer vaccines" (i.e. dendritic cell vaccination etc), those concepts have very little in common with what we currently know as vaccines and in my opinion should not be labeled as such, because they plant false ideas in the mind of the uninformed public.
 

E92 M3

Member
Can you explain why 'cancer vaccines' shouldn't be considered vaccines?

Vaccines are essentially the prepping of the immune system for a future threat. Cancer is a whole different type of metabolic process and has many different origination points.
 

GiJoccin

Member
Can you explain why 'cancer vaccines' shouldn't be considered vaccines?

the HPV vaccine is a 'cancer vaccine' - does wonders for cervical cancer

they're looked into vaccines for EBV, but it's still not clear that even if a vaccine works, if it would prevent cancer or not

but not all cancers are caused by viruses, unless that wasn't what you were confused about
 

samn

Member
the HPV vaccine is a 'cancer vaccine' - does wonders for cervical cancer

they're looked into vaccines for EBV, but it's still not clear that even if a vaccine works, if it would prevent cancer or not

but not all cancers are caused by vaccines, unless that wasn't what you were confused about

Well from what I understand 'cancer vaccines' inject material that induces the immune system to attack cancer cells. This is done in patients that already have cancer and the material injected is precisely tuned to the specific cancer present in the patient.

I'm not talking about viruses.
 
Cancer is a whole different type of metabolic process and has many different origination points.

In some cases, those vectors can be prevented by a vaccine.

Sure it's not a direct cancer vaccine, but it is effectively equivalent in the sense that vaccines against certain viral diseases will decrease the co-incidence of cancer with those diseases.
 

Nakazato

Member
I guess we will never see the rage virus from 28 days later




....

Science is fucking awesome. And for those countries that really need it this will be a godsend
 
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