I feel I am playing this game wrong. I'm playing it on the Vita. I never, ever, ever have come close to some of the ridiculous pics you all are posting. I've killeda few times now, and at most have had maybe 4 followers. Seeing all these crazy combinations, massive lists of broken upgrades...Mom's heart
Is everyone just insanely lucky, or is seed glitching the only way people know how to play? I try to get anywhere between 2-10 runs a day, depending on my schedule, and I'll be lucky if one of them has anything partly decent. Do I just need to play more, to unlock more?
Those OP builds become easier to get the better you get at the game. That said they don't come that often unless you're playing Isaac with the D6. Though the biggest factor in all of it that you can effect is securing your devil deals. Ways to help that:
-Don't take red heart damage
-Don't take boss damage
-Bomb beggars
-Get items that raise your devil deal chance (book of belial, goat head etc)
All that will raise the chance you get a devil/god deal after killing a boss, and those are the easiest ways to effect your damage.
Also becoming guppy is one of the best ways to become unstoppable. To do that you need 3 guppy pieces. Best place for those items is in your devil deals, curse rooms (always check them if you can), red chests, and secret rooms.